The production of ATP is quite a complex process, starting in the Krebs citric acid cycle (TCA cycle).
But far more important than direct ATP production are the high-energy molecules TCA provides the electron transport chain
This is where 90% of ATP is produced in aerobic metabolism.
The mitochondria are especially susceptible to nutrient deficiencies, environmental toxins, and oxidative damage.
A large amount of adenosine triphosphate (ATP) must be produced by the mitochondria every second of every day because ATP cannot be stored. This function is so important that mitochondria can take up as much as 25% of the cell volume.
Although many nutrients are necessary for ATP production. These include carnitine to transport fatty acids, iron, magnesium, manganese, and vitamins B1, B2, and B3.
There are a few strategies, to improve mitochondrial function.
This includes optimising nutrient status to limit oxygen and high-energy electron leakage in the ETC.
Decrease toxin exposure. Because of the huge metabolic activity of the mitochondria, they are especially susceptible.
Provide nutrients that protect the mitochondria from oxidative stress and utilise nutrients that facilitate mitochondrial ATP production.
Try intermittent fasting, where you fast for fixed hours of the day, which decreases energy levels in the body. To compensate, levels of NAD+ increase, which increases the ability of the mitochondria to produce ATP.
This results in a subsequent rise in ATP levels due to improved mitochondrial function.
Build some muscle mass! Even those with mitochondrial damage, such as that found in Parkinson’s disease, can increase ATP production through strength training!
Consume HMB and creatine supplements. Beta-hydroxy beta-methyl butyric acid is an active breakdown product of the amino acid leucine. It is used as a supplement to prevent muscle protein loss.
HMB and creatine supplementation in skeletal muscle cells stimulates the production of proteins and thereby increases the number of mitochondria per cell, overall improving skeletal muscle health.
If you follow these strategies, there’s no doubt that you can improve your mitochondrial health and naturally restore your mood and energy levels.
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